Selective TBK1/IKKi dual inhibitors with anticancer potency
نویسندگان
چکیده
منابع مشابه
A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency
Genotoxic drugs constitute a major treatment modality for human cancers; however, cancer cells' intrinsic DNA repair capability often increases the threshold of lethality and renders these drugs ineffective. The emerging roles of HDACs in DNA repair provide new opportunities for improving traditional genotoxic drugs. Here, we report the development and characterization of CY190602, a novel bend...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2013
ISSN: 0020-7136
DOI: 10.1002/ijc.28507